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专利名称:Preparation of oxycodone
发明人:Michael Lawrence Casner,Jen-Sen Dung,Erno
M. Keskeny,Jin Luo
申请号:US11234627申请日:20050923
公开号:US20060111383A1公开日:20060525
摘要:A process for preparing oxycodone or an oxycodone salt, wherein theoxycodone or oxycodone salt has low levels of impurities (especially 14-hydroxycodeinone) is disclosed. The process comprises the steps of: a) preparing amixture comprising oxycodone and a solvent and adjusting the pH of the mixture to lessthan 6; and subsequently b) exposing the mixture to hydrogenation reagents for a periodof at least 1 hour.
申请人:Michael Lawrence Casner,Jen-Sen Dung,Erno M. Keskeny,Jin Luo
地址:Pitman NJ US,Boothwyn PA US,Wilmington DE US,Fullerton CA US
国籍:US,US,US,US
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